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Method for In Vivo Detection of Cell-Surface Disease Markers

A pair of compatible reagents, one antibody-based biomarker target and one small molecule PET tracer, combine to provide a high affinity, disease specific detection system. Background: The medical diagnostics industry has an urgent demand for efficient non-invasive biomarkers to diagnosis and stage disease progression for cancer and Alzheimer's...
Published: 2/7/2024   |   Inventor(s): Qing Lin, Ming Fang, Gangam Kumar
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging

Bioengineering Platform for Delivery of Peptides into Cells

A platform bioengineering approach, which combines orthogonal protein crosslinking with supercharging protein surfaces, to design and develop cell-penetrating monobodies. Background: Intracellular targets, including a number of high-profile oncology-related ones, remain "undruggable". While small molecules are generally able to cross biological...
Published: 2/2/2024   |   Inventor(s): Qing Lin
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines

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