Stable Micelle Drug Formulations
Method for producing stable, concentrated drug micelles that reduce or eliminate surfactants from drug formulations.
Background:
Hydrophobic drugs comprise a substantial proportion of all pharmaceutical compounds in use today. These drugs have limited solubility in water. There are numerous strategies for addressing solubility; however, for many...
Published: 2/2/2024
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Inventor(s): Jonathan Lovell, Wentao Song, Yumiao Zhang
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology, Campus > University at Buffalo
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PCR Primers that Specifically Identify Moraxella Catarrhallis
PCR-based test to diagnose Moraxella Catarrhalis (MC) by amplifying a region of the MC chromosome and clone genes in serotype A, B and C.
M. Catarrhalis is a significant cause of human respiratory diseases and in particular is a major cause of otitis media in young children. The invention consists of PCR Primers that demonstrate quick and definitive...
Published: 2/2/2024
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Inventor(s): Anthony Campagnari, Katie Edwards, Nicole Luke-Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Campus > University at Buffalo
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A Novel Marker for Detection of Prostate Cancer
Myosine IC isoform A is overexpressed in prostate cancer tissues and metastatic cells. The monoclonal antibodies and PCR tools developed here detect overexpression. In 2012 a novel isoform of myosine IC designated isoform A was discovered. Several years later tissue distribution studies discovered it was overexpressed in prostate cancer tissues and...
Published: 2/12/2024
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Inventor(s): Wilma Hofmann
Keywords(s): Technologies
Category(s): Technology Classifications > Healthcare, Campus > University at Buffalo, Technology Classifications > Diagnostics
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Detecting a Bacterial Process in Chronic Rhinosinusitis
By looking for bacterial markers this assay distinguishes the various forms of Chronic Rhinosinusitis for quicker and more accurate clinical treatments.
Chronic Rhinosinusitis (CRS) is an inflammatory disease involving the sinuses and nasal cavity which effects 32 million in the US. Differentiation between chronic and acute sinusitis would allow...
Published: 2/2/2024
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Inventor(s): Jens Ponikau, Hirohito Kita, David Sherris
Keywords(s): Technologies
Category(s): Technology Classifications > Screens and Assays, Campus > University at Buffalo, Technology Classifications > Diagnostics
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Small Molecule Imaging of Fungi by PET Scanning
Isotopically-labeled calcofluor derivatives to differentiate fungal lung infections from bacterial or cancer nodules in immunosuppressed patients by PET scanning. This relates to the field of radioactive, isotopically-labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi including Aspergillus species, such as by...
Published: 2/2/2024
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Inventor(s): John Panepinto, Peter Williamson, Dale Kiesewetter, Jin Qiu
Keywords(s): Technologies
Category(s): Technology Classifications > Research Tools and Reagents, Campus > University at Buffalo, Technology Classifications > Diagnostics
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Monoclonal Antibody 3F5-5E5 and P107 Diagnostic Markers and Putative Vaccine Antigen for Moraxella Catarrhalis and Supplemental Mab 4G5
Monoclonal antibodies, proteins, nucleic acid sequences and lipoologosaccharides specific to Moraxella catarrhalis. These materials are useful for designing a much-needed diagnostic test. This invention includes monoclonal antibodies, proteins, nucleic acid seqeunces and lipoologosaccharides (LOS) which are specific to Moraxella catarrhalis. These...
Published: 2/2/2024
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Inventor(s): Anthony Campagnari, Kristin Furano, Amy Howlett, Nicole Luke-Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Research Tools and Reagents, Campus > University at Buffalo, Technology Classifications > Diagnostics
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