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Alternative to Antibody Drug Conjugates

Antibody Drug Complexes (ADCx) that serve as potentially safer alternatives to traditional Antibody Drug Conjugates (ADCs). Background: While ADCs have seen some success in the market, toxicity issues have limited the class from reaching its full potential. Toxicity of these agents stems from exposure of their payloads (e.g. auristatin), primarily...
Published: 3/8/2024   |   Inventor(s): Brandon Bordeau, Joseph Balthasar
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Antibodies, Technology Classifications > Drug Delivery

Stable Micelle Drug Formulations

Method for producing stable, concentrated drug micelles that reduce or eliminate surfactants from drug formulations. Background: Hydrophobic drugs comprise a substantial proportion of all pharmaceutical compounds in use today. These drugs have limited solubility in water. There are numerous strategies for addressing solubility; however, for many...
Published: 2/2/2024   |   Inventor(s): Jonathan Lovell, Wentao Song, Yumiao Zhang
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology, Campus > University at Buffalo

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