Targeted delivery of dopamine transporter genes to dopamine neurons (MTA)

Description:

Adeno-associated viruses (AAVs) were created to specifically deliver genes to dopaminergic neurons.  The proof-of-principle experiment delivered DAt under the control of a tyrosine hydroxylase promoter in a mouse model of dopamine deficiency syndrome (DTDS).

Patent Information:
For Information, Contact:
Michael Fowler
Commercialization Manager
University at Buffalo
716-645-8136
mlfowler@buffalo.edu
Inventors:
Caroline Bass
Patrick Fuller
Raul Gainetdinov
Keywords:
Technology
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