Virus-Like Particles for mRNA delivery
Virus-like particles have been engineered for drug delivery, gene editing applications, mRNA delivery and overcoming barriers in mouse lungs.
Background:
Recent biomedical research has shown increased interest in the use of virus-like particles as a drug delivery vehicle. Current viral vectors have been shown to cause adverse immunological responses,...
Published: 5/19/2025
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Inventor(s): Sriram Neelamegham, Qi Yang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Gene Therapy, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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A New Anti-triple Negative Breast Cancer Agent
A unique heat-labile enterotoxin cytotoxic to triple-negative breast cancer (TNBC) cells with reduced side effects.
Background:
Approximately 10-15% of all breast cancers are triple negative, lacking the estrogen or progesterone receptors and the human epidermal growth factor receptor 2 (HER2). TNBC is an aggressive form of cancer with a poorer...
Published: 5/13/2025
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Inventor(s): Terry Connell, Natalie King-Lyons, Hesham Nawar
Keywords(s): Featured, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines
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ePassport™ System
A user friendly system to track education training compliance of students, gather supervisors’ approval and generate reports for accreditation boards.
Background:
Students in professional schools are often required to complete a series of tasks at varied times. For instance, medical students need to observe or perform a certain procedure....
Published: 5/13/2025
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Inventor(s): Mark Schneggenburger, Tanya Biscardi
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Education and Training, Technology Classifications > Information Technology
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Borophene Tubes
Nanotubes directly synthesized from atomically thin sheets of borophene to adopt multiple structures with high thermal and electrical conductivity.
Background:
Borophene nanotubes (BNT) have been a synthetic goal for decades based on predictions of their usefulness in energy storage and generation. BNTs offer options for carbon nanotubes applications,...
Published: 5/13/2025
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Inventor(s): Paras Prasad, Mark Swihart, Pranay Ranjan, Devendra Negi, Amitava Banerjee, Shahzad Ahmad, Moin Siddiqui, Arshiya Ansari, Ghanshyam Varshney
Keywords(s): Chemistry, Featured, Materials & Chemicals, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Materials and Chemicals, Technology Classifications > Engineering
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Ga₂O₃ Vertical MOSFET for Enhanced Power Management
A vertical trench MOSFET using a unique in-situ Mg-doped current blocking layer to enable high-voltage operation with enhanced efficiency and robustness in power electronic devices.
Background:
This technology addresses the need for high-voltage power devices suitable for grid and traction applications, overcoming the limitations of traditional silicon-based...
Published: 5/13/2025
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Inventor(s): Uttam Singisetti, Hongping Zhao, Sudipto Saha, Lingyu Meng, Dong Yu
Keywords(s): Featured, Semiconductor and Microprocessing, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Energy, Technology Classifications > Electronics
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Device and Methods for Telehealth Wound Care
An inexpensive, hand-held optical device capable of imaging wounds for telehealth monitoring of healing and vascular structure.
Background:
Open sores and wound healing are a pressing concern in medical care of limited mobility patients. For instance, diabetic foot ulcers are associated with a 25% five year mortality rate as well as other complications....
Published: 5/13/2025
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Inventor(s): Wenyao Xu, Jun Xia, Alexander Gherardi, Tianyu Chen
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging
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Development of Lectins with Protein Engineering
Lectins that exclusively bind sialylated core-2 O-linked glycans within cancerous tissue with a higher affinity than physiologically healthy tissue.
Background:
Lectins bind complex carbohydrates on cell surfaces and secreted glycoproteins. These carbohydrates are modified during disease from altered metabolism, though the proteins themselves are...
Published: 5/13/2025
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Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Secure Multi-Source Key Dissemination Using Network Coding
A secure key-cast network design to ensure positive-rate key dissemination while preventing non-terminal nodes from accessing information.
Background:
In cryptographic applications, disseminating a secret key among network nodes while ensuring that non-terminal nodes do not gain any information about the key is a critical challenge. This concept,...
Published: 5/13/2025
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Inventor(s): Michael Langberg, Michelle Effros
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Computers, Technology Classifications > Information Technology
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Self-Sustained Hydrogen Production
A self-sustained compact reactor for continuous hydrogen gas production from ammonia decomposition.
Background:
Hydrogen offers advantages as a clean and safe fuel for broad applications, but its storage and transport are expensive. Conversely, ammonia is an effective hydrogen carrier, as it contains 17.6% hydrogen by weight and can be economically...
Published: 5/13/2025
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Inventor(s): Amr Ibrahim, Miao Yu, Sung Hwan Park, Saman Emami Gerami
Keywords(s): Chemistry, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications, Technology Classifications > Energy, Technology Classifications > Engineering, Technology Classifications > Instrumentation, Technology Classifications > Materials and Chemicals
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Device and Method for Wound Monitoring and Diagnosis using Radio-Frequency Technologies
A device to monitor wound healing non-invasively without disturbing the dressing to reduce the risk of infection and complications.
Background:
Chronic wound healing affects nearly 6 million Americans per year at a cost of $20 billion. Proper wound healing needs to be monitored in many patients including burn victims as well as pressure venous leg...
Published: 5/13/2025
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Inventor(s): Wenyao Xu, Jun Xia, Xiaoyu Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging
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