Novel Test for Non-HLA-based-rejection in Organ Transplantation
Luminex-based immunoassay for prediction of non-HLA determinants of kidney transplant graft rejection
Background:
End-stage kidney disease, also known as end-stage renal disease or kidney failure, affects over 800,000 people in the US. It is rapidly fatal without treatment, but can be treated palliatively with dialysis or curatively by kidney transplant....
Published: 6/10/2026
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Inventor(s): Lakshmanan Suresh, John Tomaszewski
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays
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Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations.
Background:
Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 5/13/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
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Production of Salivary Gland Epithelial Progenitors and Acinar Organoids
Human iPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function.
Background:
Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 5/13/2026
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Inventor(s): Stelios Andreadis, Ronel Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays
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Fluorescent Peptides for Membrane Tension Reporting and Biomarkers
A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension.
Background:
The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...
Published: 5/15/2026
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Inventor(s): Thomas Suchyna, Sergei Sukharev
Keywords(s): Featured, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials
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Simulation-Based Wildfire Spread Modeling Tool for Community-Scale Risk Assessment (SWUIFT)
This technology enables community-scale wildfire risk assessment using a simulation-based model that predicts fire spread and damage wihtin the wildland-urban interface, supporting proactive mitigation and emergency planning.
BACKGROUND:
Communities and infrastructure owners currently lack effective tools to estimate wildfire spread and resulting...
Published: 4/24/2026
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Inventor(s): Negar Elhami-Khorasani, Fernando Szasdi-Bardales, Nima Masoudvaziri
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Agriculture, Technology Classifications > Environment
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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)
This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription.
BACKGROUND:
Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 4/16/2026
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Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics
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Determining the Percentage of Recycled Plastic Content in a Plastic Product
A device to determine the percentage of recycled plastic content in a manufactured plastic product.
BACKGROUND:
As global plastic waste continues to rise, accurately identifying and quantifying recycled content in plastic products is critical for developing a circular economy. At present, there is no method that can accurately determine the percentage...
Published: 4/30/2026
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Inventor(s): Amit Goyal, Thomas Thundat, Yaoli Zhao, Charuvahan Adhivarahan, Karthik Dantu, Chandra Lekha Jyothula
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Sensors
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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties
BACKGROUND:
The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Apelin-Receptor (APJ) Antagonists
A series of stable, small molecule compounds that inhibit an alternative (non-VEGF) angiogenic pathway that is overexpressed in a variety of cancers.
Background:
Antiangiogenic drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway are widely used to treat solid tumors and ocular conditions such as wet AMD. However, anti-VEGF...
Published: 4/16/2026
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Inventor(s): Youngjae You, Sukyung Woo, Ganesh Bist, Ahmed Elsheikh
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Design and Synthesis
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Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers
BACKGROUND:
There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials.
TECHNOLOGY...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
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