Development of Lectins with Protein Engineering
Lectins that exclusively bind sialylated core-2 O-linked glycans within cancerous tissue with a higher affinity than physiologically healthy tissue.
Background:
Lectins bind complex carbohydrates on cell surfaces and secreted glycoproteins. These carbohydrates are modified during disease from altered metabolism, though the proteins themselves are...
Published: 11/20/2024
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Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Self-Sustained Hydrogen Production
A self-sustained compact reactor for continuous hydrogen gas production from ammonia decomposition.
Background:
Hydrogen offers advantages as a clean and safe fuel for broad applications, but its storage and transport are expensive. Conversely, ammonia is an effective hydrogen carrier, as it contains 17.6% hydrogen by weight and can be economically...
Published: 11/18/2024
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Inventor(s): Amr Ibrahim, Miao Yu, Sung Hwan Park, Saman Emami Gerami
Keywords(s): Chemistry, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications, Technology Classifications > Energy, Technology Classifications > Engineering, Technology Classifications > Instrumentation, Technology Classifications > Materials and Chemicals
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Modified Graphene Oxide-based Membranes for Mixture Separations
A facile method for developing membranes for hydrocarbon mixture separations by depositing graphene oxide flakes on a commercial porous substrate.
Background:
Molecular separations in mixtures account for approximately 50% of industrial energy use in the US alone, so there is high demand for alternate separation technologies, particularly for liquid...
Published: 4/10/2024
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Inventor(s): Miao Yu, Bratin Sengupta
Keywords(s): Chemistry, Featured, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations.
Background:
Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 3/6/2024
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Featured, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
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ALD-enabled High-Performance Membranes for Gas Separation
Polymer-based membranes developed with high H2/CO2 selectivity using facile surface nanoengineering for higher energy efficiency and lower cost production.
Background:
Isolation of CO2 from mixtures containing H2 is a critical gas separation, producing 94 million metric tons of H2 worldwide and valued at $170 billion in 2021. This market will continue...
Published: 7/9/2024
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Inventor(s): Haiqing Lin, Won-IL Lee (Stonybrook), Chang-Yong Nam (non-UB), Leiqing Hu, Kim Kisslinger(non-UB), Vinh Bui, Ashwanth Subramanian(non-UB)
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Clean Energy, Technology Classifications > Environment
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Benzodiazepinone-derived Inhibitors of EGFR and HER2
A class of benzodiazepinone-derived molecules, inhibitors of both triple mutant EGFR and HER2, for cancer therapeutics or biochemical research tools.
Background:
Inhibition of epithelial growth factor receptor (EGFR) as a non-small cell lung cancer (NSCLC) therapeutic is not a new concept, but 75% of patients die within five years of diagnosis. As...
Published: 6/26/2024
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Inventor(s): David Heppner, Stefan Laufer, Florian Wittlinger, Blessing Ogboo, Calvin Pham, Alexander Rasch
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Materials and Chemicals
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High Silica Pd/Catalysts with Enhanced Low Temperature Methane Oxidation Performance
Pd-based silica (Si/Al > 50) small pore zeolite catalysts with increased durability and improved low temperature CH4 oxidation performance (> 90% CH4 conversion at temperatures < 400ºC).
Background:
Natural gas has garnered attention as a cleaner alternative fuel for vehicles compared to gasoline or diesel. Natural gas vehicle (NGV)...
Published: 10/28/2024
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Inventor(s): Tala Mon, Jingzhi Liu, Chih-Han (Judy) Liu, Junjie Chen, Viktor Cybulskis, Eleni Kyriakidou
Keywords(s): Environment, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
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Polymorphs of Nicotine Salts
Novel crystalline polymorphs of nicotine salts with tunable properties and potential for use as sublimated products
Background:
Nicotine salts such as those used in e-cigarettes (i.e. vaping devices) deliver nicotine to users similar to the way a traditional cigarette does and are easier to inhale than freebase nicotine. The nicotine salts used in...
Published: 7/9/2024
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Inventor(s): Jason Benedict, Devin Angevine
Keywords(s): Technologies
Category(s): Technology Classifications > Materials and Chemicals
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Dative Epitaxy - Growing Semiconductor Materials on vdW Templates
This is a distinct form of thin film epitaxy utilizing dative bonds used to grow semiconductor crystals with single unit cell thickness on a thin layer vdW template.
Background:
Two-dimensional (2D) semiconductors are the core force of next-generation electronics and optoelectronics, which are expected to exhibit quantum effect and greatly improve...
Published: 10/23/2024
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Inventor(s): Hao Zeng, Mengying Bian
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Computers
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Nature-inspired Functionally-graded UHMWPE + Kevlar Composites Achieve Extraordinarily High Strength
Nature-inspired polymers are achieved using unique processing to yield functional gradient composites with embedded Kevlar fibers exhibiting extraordinarily high strength lightweight UHMWPE materials.
Background:
Demand for new energy absorption materials and implantable polymeric biomaterials has increased significantly in recent years. The...
Published: 10/17/2024
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Inventor(s): Shenqiang Ren, Lu An
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Technology Classifications > Engineering
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